Lifestyle

Feds warn of 14 infant deaths in rockers from Fisher-Price, Kids2

At least 13 infant deaths have been reported in Fisher-Price’s Infant-to-Toddler Rockers and Newborn-to-Toddler Rockers since 2009, while there has been one death reported with a Kids2 Bright Starts Rocker, the U.S. Consumer Product Safety Commission (CPSC) and both companies warned in new alerts issued Tuesday. Rockers should never be used for sleep, and infants […]

Lifestyle

Novel radiopharmaceutical pair detects and treats melanoma, shows potential for broad application in solid tumors

A newly developed small-molecular radiopharmaceutical pair has successfully visualized and treated melanoma in a preclinical study, according to new research presented at the Society of Nuclear Medicine and Molecular Imaging 2022 Annual Meeting. Targeting a receptor that is aberrantly overproduced in many human solid tumors, this theranostic (therapy + diagnostic) approach shows promise for non-invasive […]

Lifestyle

Targeted radionuclide treatment achieves high response rate, minimal toxicities for advanced-stage neuroendocrine tumors

A targeted radionuclide alpha therapy, 225Ac-DOTATATE, has been shown to have long-term anti-tumor effects in patients with advanced-stage gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Results from the Phase II study showed promising survival rates, high response rates and an acceptable toxicity profile, making 225Ac-DOTATATE a potential treatment option for patients who have exhausted other forms of therapy. […]

Lifestyle

Researchers describe characteristic behaviors of erythropoietin-producing kidney cells

A research team at Kyoto University has revealed characteristic behaviors of erythropoietin (Epo)-producing cells. Epo is a hormone produced by the kidney that stimulates red blood cell production. The discovery provides further insight into the mechanism of renal anemia, a common complication of chronic kidney disease—low red blood cell count—which is caused by renal insufficient […]

Lifestyle

Atogepant prevents migraine in adults

Richard B. Lipton, M.D., from Albert Einstein College of Medicine and the Montefiore Headache Center in New York City, and colleagues evaluated the efficacy and safety of atogepant for the preventive treatment of migraine from Dec. 14, 2018, to June 19, 2020, in adults seen at 128 U.S. sites with four to 14 migraine-days per […]

Lifestyle

Early-life exposure to air pollution causes changes in brain connectivity in preadolescents

Higher exposure to air pollution is associated with higher functional brain connectivity among several brain regions in preadolescents, while exposure to traffic noise was not, according to a study led by ISGlobal. The findings also identify the first years of life as the most sensitive period of exposure to air pollution. Traffic-related air pollution and […]

Lifestyle

Study identifies therapeutic targets for Alzheimer’s disease

A new University of Kentucky College of Medicine study has identified potential targets to develop a therapy that could prevent Alzheimer’s disease. Alzheimer’s disease is the most common form of dementia, affecting an estimated 6.2 million Americans in 2021 according to the Centers for Disease Control and Prevention. Currently, there is no cure, only pharmaceutical […]